Fenben is a widely used deworming medicine in cattle and a broad-spectrum anthelmintic. It belongs to a group of drugs called the “benzimidazole carbamate” class and it has been in human use for about 50 years. It has been shown to have anti-cancer properties in lab testing but turning these tests into a human cancer treatment is a long journey. A veterinarian who made videos claiming that the drug could cure cancer has been debunked by McMaster researchers.

The anecdotal success stories of this approach have led many cancer patients to attempt it. But randomized controlled trials involving large numbers of people are needed to determine whether this is a viable strategy.

Scientists have also studied fenbendazole for cancer in lab experiments and mice, and they’ve found that it can help kill cancer cells in the laboratory. It works by disrupting microtubules in cancer cells, causing them to shrink and die. In addition, it seems to prevent cancer cells from absorbing sugar, a process known as glycolysis, which is necessary for their survival.

One researcher reported that fenbendazole was effective at stopping the growth of human colorectal cancer cells in a lab dish. It did so by blocking the expression of GLUT transporters and inhibiting hexokinase, which are necessary for glucose uptake into cancer cells. The drug also caused the activation of the autophagy pathway by increasing Beclin-1 expression in these cells.

Another research team investigated fenbendazole for cancer by feeding it to mice with colon cancer. After 12 days of treatment, researchers weighed the tumors and observed that they had decreased in size. They also found that the fenbendazole had reduced the activity of tumor-promoting enzymes in these mice, which is a sign that it could be an effective cancer therapy.

Some of the anecdotal fenben for cancer successes may be due to other factors, such as conventional treatments, which aren’t being accounted for in these reports. But researchers believe that if more people try the fenben for cancer protocol, more evidence will be generated to support it.

Ultimately, scientists are hoping that fenbendazole will be added to the arsenal of available drugs against this disease. In fact, a 2022 study examined different combinations of fenbendazole and vitamins to see which regimens were best for reducing tumor volume in mice with lymphoma. The results indicated that a combination of fenbendazole and a vitamin-rich diet produced the most significant tumor reduction. fenben cancer treatment

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