Can Fenben For Cancer Cure Pancreatic Cancer?

Although some anecdotal reports suggest fenben for cancer can cure the disease, there are many factors that aren’t being taken into account. Tippens was enrolled in a clinical trial when he started taking fenben and was also receiving other conventional cancer treatments, so it’s difficult to determine whether his improvement could be attributed to fenben alone.

While there is limited research on fenben for cancer, several studies have shown it can slow the growth of tumors in cell cultures and animals. It appears that fenben disrupts microtubules, which helps to prevent cell division. In addition, fenben may inhibit the growth of cancer cells by reducing their glucose consumption. Cancer cells use a lot of glucose for energy, which is why they grow so quickly. Fenbendazole restricts glucose uptake by blocking expression of the GLUT transporters and hexokinase 2 enzyme, starving cancer cells of the division-enabling sugars.

Fenbendazole also causes apoptosis in 5-FU-sensitive SNU-C5 and SNU-C5/5-FUR CRC cells by increasing p53 expression and partially via necrosis, autophagy and ferroptosis (Fig. 8A). Moreover, the drug significantly reduced tumor vascularity in these mice by lowering hemoglobin levels in the tissues.

While the results from animal studies show promise for fenben for cancer, human trials would need to be performed to confirm its effectiveness. Currently, the only two small clinical studies that have been completed with fenbendazole are in the context of treating parasites. Until we have the results of randomized controlled trials involving people with pancreatic cancer, it’s difficult to say whether this antiparasitic drug can indeed treat the disease. fenben for cancer